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태수술에 대한 이해와 구순구개열 환자에서의 적용
Understanding of Fetal Surgery and Application to the Cleft Lip and Palate Patient

대한구순구개열학회지 2008년 11권 2호 p.49 ~ 58

김성민, 박정민, 명훈, 최진영, 이종호, 정필훈, 김명진,

소속 상세정보

김성민 ( Kim Soung-Min ) - 서울대학교 치과대학 구강악안면외과학교실
박정민 ( Park Jung-Min ) - 강릉대학교 치과대학 구강악안면외과학교실
명훈 ( Myoung Hoon ) - 서울대학교 치과대학 구강악안면외과학교실
최진영 ( Choi Jin-Young ) - 서울대학교 치과대학 구강악안면외과학교실
이종호 ( Lee Jong-Ho ) - 서울대학교 치과대학 구강악안면외과학교실
정필훈 ( Choung Pill-Hoon ) - 서울대학교 치과대학 구강악안면외과학교실
김명진 ( Kim Myung-Jin ) - 서울대학교 치과대학 구강악안면외과학교실

KMID : 0952820080110020049

Abstract

The development of fetal surgery has led to promising options for many congenital malformations, such as congenital diaphragmatic hernia (CDH), obstructive uropathy, twin-to-twin transfusion syndrome (TTTS), and sacrococcygeal teratoma. However, preterm labor (PTL) and premature rupture of membranes continue to be uniquitous risks for both mother and fetus. To reduce maternal morbidity and the risk of prematurity, minimal access techniques were developed and are increasingly employed recently. Lift-threatening diseases as well as severely disabling but not life-threatening conditions are potentially amenable to treatment. Recently, improvement of video-endoscopic technology has boosted the development of operative techniques for feto-endoscopic surgery, which has been demonstrated to be less invasive than the open approach. Fetal surgery for repair of cleft lip and palate, a congenital anomaly which is not life threatening, is inappropriate until such time that the benefits are shown to outweigh the risks of both the procedure itself and preterm delivery. Further animal studies will be needed before intrauterine surgery for humans should be considered. For the better understanding of recent techniques and complications associated with fetal intervention of congenital facial defect patients, we reviewed recent related articles about the current knowledge and new perspectives of experimental fetal fetal surgery in the cleft lip and palate defects.